WebBTG2. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … WebSep 23, 2024 · BTG2 and YY1 may be crucial therapeutic targets to intervene in metabolic dysfunction in response to the GH-dependent signaling pathway. ... J. A. et al. Inhibition of breast cancer invasion by ...
MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2
WebMultivariate Cox proportional hazard regression analysis revealed that BTG2 mutations dominated the death risk of PT-DLBCL patients, with hazard ratios in the range of 95% CI 1.15 to 4.3311 (HR, 2.23, P =0.007). The median OS was 28 months in the BTG2 mutation group and 65 months in the BTG2 wt group ( Figure 6A ). WebMar 7, 2024 · IntroductionLung adenocarcinoma (LUAD), as the most frequent pathological subtype of non−small cell lung cancer, is often characterized by poor prognosis and low 5-year survival rate. Exploriton of new biomarkers and accurate molecular mechanisms for effectively predicting the prognosis of LUAD patients is still necessary. Presently, BTG2 … datacenter valor
Effects of BTG2 on Proliferation Inhibition and Anti-Invasion in …
WebJun 16, 2010 · BTG2 is known to mediate chemotherapy induced apoptosis in cancer cells [29–31] and a study by Lim et al. indicates that BTG2 enhances cancer cell death by accumulation of H 2 O 2 . Down-regulation of BTG2 has been observed in several cancer types such as prostate cancer, breast cancer and gliomas [17, 18, 33]. In this study … WebMar 21, 2024 · Elevated BTG2 improves the radiosensitivity of non-small cell lung cancer (NSCLC) through apoptosis. Zhu C, et al.Thorac Cancer, 2024 May. PMID 35388633, Free PMC Article MicroRNA miR-92a-3p regulates breast cancer cell proliferation and metastasis via regulating B-cell translocation gene 2 (BTG2). Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the precursors of cerebellar granule neurons. This demonstration was … See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with Pax6 and Tbr2 when observing the role of Tis21 in neurogenic divisions. See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more datacenter usage