Webb23 nov. 2024 · Research History. For nearly 20 years, controversy has followed, primarily from a prospective multicenter trial testing mild therapeutic hypothermia versus normothermia in survivors of out-of-hospital cardiac arrest.1 This prominent trial identified a risk ratio of 1.40 favoring good neurological outcome in the hypothermia group, along … Webb27 apr. 2016 · With the results from several basic and clinical studies, targeted temperature management (TTM) including therapeutic hypothermia (TH) have been recognized as …
Fever and therapeutic normothermia in severe brain injury …
Webb18 jan. 2013 · This is a core temperature over 38°C. Fever is a type of hyperthermia caused by an elevation of the thermoregulatory set point by a process such as infection and is defined as a core temperature >38.3°C (101°F). Hyperpyrexia is a very high temperature ≥40°C that is considered life-threatening when ≥41.5°C. Webb10 feb. 2024 · After treatment with either normothermia (NT) or therapeutic hypothermia (TH), we observed a significantly enhanced expression level of the NETosis marker Citrullinated H3 (Cit-H3), which was significantly more pronounced in animals treated with TH than in those treated with NT. hover show text tailwind
Confusion Around Therapeutic Temperature Management ... - Circulation
Webb16 jan. 2024 · Ueda Y, Oda Y, Povlishock J and Wei E (2024) Mechanisms Associated with the Adverse Vascular Consequences of Rapid Posthypothermic Rewarming and Their Therapeutic Modulation in Rats, Therapeutic Hypothermia and Temperature Management, 10.1089/ther.2024.0022, 10:4, (204-210), Online publication date: 1-Dec-2024. WebbTherapeutic hypothermia or targeted temperature management (TTM) following cardiac arrest has been shown to attenuate neurologic damage and improve survival. Recent evidence has shown similar outcomes between cooling the patient to 32-34 C for 24 hours and maintaining normothermia. No significant benefit has been found for the Webb18 nov. 2024 · Table 3: Modalities of Temperature Management Used Among Both Groups Author’s Conclusions: Among patients with coma who had been resuscitated from cardiac arrest with non-shockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable neurologic outcome … hover show div